Pregnancy test after hCG injection 1500. HCG injection when excreted from the body. HCG shot to stimulate ovulation. Chorionic gonadotropin for men

Description - how long does it take for pregnyl 1500 to be removed from urine

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Chorionic gonadotropin 1500 units

Chorionic gonadotropin 1500 is a drug that, due to its gonadotropic action, stimulates the maturation of follicles in the ovaries, and also maintains the corpus luteum phase. A drug is produced in the form of a lyophilisate, on the basis of which a solution for intramuscular administration is prepared. One vial contains the active substance chorionic gonadotropin 1500 units.

The drug is packaged in glass vials. The lyophilisate itself is in the form of a white powder. Each package also contains a special component with which the active substance is diluted - sodium chloride, in a volume of 1 milliliter. During production, the drug is laid out in cellular blisters, and five such sets are put into each pack.

Pharmacological features

Chorionic gonadotropin (1500 units) is classified as a hormone of the gonadotropic type, which in the natural environment is produced by the placenta, after which it is released into the urine. Subsequently, when the hormone is extracted, it is sent for purification.

HCG is necessary to maintain the process of development and formation of the placenta in a normal state, and is also a stimulant for the corpus luteum to start producing the hormone estrogen. As mentioned earlier, the remedy is characterized by a luteinizing and gonadotropic effect.

1500 gonadotropin is a powerful stimulator of estrogen and progesterone production in female patients, and also provokes ovulation.

If the drug is prescribed to the representatives of the stronger sex, then they improve the process of spermatogenesis, as well as more high level there is a stimulation of the production of sex hormones of the steroid group.

With cryptorchidism, the remedy has the ability to provoke testicular descent.

The drug is characterized by a high degree of absorption after intramuscular injection has been performed. According to some reports, before excretion, the active component passes through the kidneys, where it is modified in the body. Answering the question: after what time hCG 1500 is excreted from the body, doctors call the period from five days to a week.

Pharmacokinetic properties

Patients are often interested in how long an injection of hCG 1500 is excreted from the body. The manufacturer indicates that the half-life is 8 hours. It is possible to track the maximum level of concentration of the active substance in the blood plasma 4-12 hours after the injection.

If you regularly inject hCG 1500 units, after how much it is excreted from the body, you will need to check with the doctor, since on average this process takes 29-30 hours, but the active component tends to accumulate. About 10-20% of human chorionic gonadotropin can be found unchanged in the urine, the rest is excreted by the kidneys in the form of fragments of the beta chain.

Indications

There are certain conditions of the body, upon detection of which doctors may prescribe intramuscular injection of human chorionic gonadotropin in the dosage in question, among them:

Insufficiency of the luteal phase - this is necessary in order to be able to support the functioning of the corpus luteum of the ovary;
Provocation of the onset of ovulation is often practiced when solving infertility problems, as well as when it is necessary to stabilize the cycle.

The representatives of the stronger sex are also prescribed hCG 1500 units.

The drug will have a certain therapeutic efficacy in the presence of the following diseases: in gonadotropic gonadism, as part of complex therapy, when a drug of human menopausal gonadotropin is taken, in cryptorchidism, to assess the functionality of the testicles, and also if it is necessary to conduct a Leydig functional test.

Contraindications

Like most drugs, to hCG 1500 units. instructions for use contains certain contraindications. So, for example, it is unacceptable to take a medication if the patient is diagnosed with neoplasms that can change when certain hormones enter the body.

It is also unacceptable to prescribe a remedy for organic cryptorchidism, when the patient has an anatomically incorrect location of the testicles, their localization is changed after the operation, or due to the presence of an inguinal hernia. Also, a contraindication to the beginning of therapy is the individual intolerance of the drug by the body.

Dosage

The drug is intended for intramuscular injection. Initially, the lyophilisate is diluted in the form of a powder with a special filler, after which the solution is drawn into a syringe and a slow injection is made. The dosage may be adjusted by the attending physician depending on the purpose of the drug.

During menstrual cycles in women who pass without ovulation, 6-7 injections of Chorionic gonadotropin are indicated, with an interval of one day. For maintenance therapy of the corpus luteum phase, the scheme provides for 2-3 injections within nine days after the onset of ovulation or embryo transfer.

In the case of observation in adolescents of delayed puberty, which occurs due to insufficiency of the gonadotropic function of the pituitary gland, injections of the drug are indicated with a frequency of 2-3 times a week for six months.

With cryptorchidism, which is not caused by anatomical obstruction, patients aged 3-6 years are given the drug 2 times a week. If necessary, the treatment can be repeated.

After the women were given an injection of hCG 1500, when the test should be done, the attending physician should tell. The day may vary depending on the amount of time the injection was performed medicinal product and for what purpose it was intended.

On average, the test after an injection of hCG is 1500 units. do for 3-6 days. In some cases, if there is no pregnancy, a second, barely noticeable, strip may appear. With a successful conception on the eighth day, it will gradually begin to become brighter.

To confirm pregnancy, they do tests and donate blood for hCG in dynamics.

Side effects

Depending on gender and age, negative reactions may have different kind. Least of all, doctors recorded the presence of generalized rashes and a state of fever in patients. Significantly more often, reactions of a local type were noticed, including: pain and bruising at the injection site, itching, redness, swelling of the skin, increased fatigue.

In women after injections, reactions can give nervous system which manifests itself in the form of dizziness and pain. It is also possible that the development depressive states, irritability and anxiety. In certain cases, edema may appear.

In the representatives of the stronger sex, after injections of chorionic gonadotropin, rashes in the form of acne often appear on the skin of the face. In certain cases, the process of puberty is accelerated, the penis enlarges, prostate hyperplasia is observed, the sensitivity of the nipples increases, and the testicles in the inguinal canal increase.

Overdose

The drug in question is different low level toxicity. If it has been exceeded allowable dose medications, then the fairer sex may develop signs of ovarian hyperstimulation syndrome.

Representatives of the stronger sex, with improper use of the drug, can also observe symptoms of an overdose: a change in the anatomical appearance of the pectoral muscle (mammary gland), if long time treatment was carried out aimed at eliminating such a pathology as the absence of a testicle in the scrotum, the boys begin to behave as if they are again experiencing the first stage of puberty, a decrease in the number of spermatozoa, the initial stage of the process of destruction of the seminiferous tubules.

special instructions

In the course of treatment with this drug, doctors note an increased risk of developing a pathology such as thromboembolism of the veins or arteries, as well as their combination.

That is why, those women who are at risk, before starting therapy, should carefully evaluate its benefits over possible dangers, especially if in vitro fertilization is to be performed.

The gynecologists themselves draw the attention of women to the fact that the process of bearing a child is in itself associated with an increased risk of developing varicose veins and thrombosis.

It is also possible that after the treatment, a woman may have a multiple pregnancy.

During the entire course of drug administration, as well as within one and a half weeks after completion of therapy, the drug affects immunological tests.

Due to the fact that the concentration of the hCG hormone in the blood plasma increases, a false-positive definition of pregnancy is not excluded.

When treating patients of the stronger sex, there is a possibility of increasing their own production of androgens in the body, therefore, those men who are at risk should take the drug exclusively for medical reasons and under medical supervision.

Therapy may not give proper results if a woman has a high concentration of follicle-stimulating hormone in the body. With prolonged treatment, antibodies to the drug are formed. If the treatment of cryptorchidism is unreasonably long, then degeneration of the mammary glands will occur.

During the period of treatment, you should abandon the management of motor transport, as well as work with complex mechanisms. During pregnancy and lactation, the drug is contraindicated for use. Do not prescribe medicine to patients who have not reached the age of three.

Source: https://1ivf.info/ru/other/khorionichesky-gonadotropin-1500

HCG injection: how long will ovulation be, when to do the test, whether pregnancy has occurred

Chorionic gonadotropin is a hormone necessary for the fertilization of the egg and the maintenance of pregnancy. Sometimes a woman's body produces too little hCG, which prevents her from getting pregnant. Then synthetic analogues of the hormone are used in the form of an injection.

When appointed

HCG preparations made from proteins in the urine of pregnant women. The hormone stimulates the synthesis of progesterone and estrogen - the main hormones that help form the corpus luteum and attach the embryo to the uterine wall, and then keep the fetus until the placenta is formed.

Preparations available as a solution for injection, have the following names: Pregnil, Menogon, Novarel. An injection is made into the abdomen with a syringe with a short insulin needle.

HCG injections stimulate the ovulatory process, they are used for the following pathologies:

Dysfunction of the ovaries, which occurs due to a malfunction of the hypothalamus and pituitary gland.
Dysmenorrhea (menstruation, accompanied by severe pain, dizziness, weakness).
Infertility, which is anovulatory in nature. That is, there is no dominant follicle.
Insufficient level of functioning of the corpus luteum.
Miscarriage (permanent miscarriages or missed pregnancy).
Preparation for in vitro fertilization.
Maintenance of pregnancy.
Stimulation of ovulation.

For the use of such a means of stimulation, there are contraindications:

Various tumors, cysts in the ovaries.
Early menopause.
Lactation.
Obstruction of the fallopian tubes.
Diseases of the adrenal glands.
Tendency to thrombosis.
Individual intolerance.

Important! Patients with heart and kidney failure are prescribed hormones only after a thorough examination!

If a woman has impaired egg maturation, then ovulation does not occur. The reason for this is: polycystic, tumors, prolonged stress. The following situations usually occur:

The follicles do not mature at all.
The follicles do not fully mature.
The follicle matures, but the egg does not leave the corpus luteum.

The hCG injection is designed to help the formation of the follicle and stimulate the release of the egg.

Before using the hormone, a woman undergoes an examination:

Tests for hormone levels.
Examinations for patency of pipes.

The hormone is then injected when on ultrasound the doctor determined the development of the dominant follicle at a dosage of 1500-5000 units to stimulate its growth. To stimulate super ovulation in preparation for IVF, hCG is administered once in the amount of 10,000 units.

ovulation must occur 24-36 hours after injection. The process is controlled by ultrasound. If ovulation does not occur, then next cycle increase the quantity. The exact dosage is determined by the doctor for each specific case.

Important! Self-appointment prohibited hormone therapy this can lead to serious health consequences.

After, how the follicle burst and the egg was released, to further maintain her vitality and ability to fertilize, the doctor prescribes hCG injections.

Injections are placed on the 3rd, 6th and 9th days after ovulation at a dosage of 5000 units. This is necessary to maintain the corpus luteum and help the embryo attach.

During pregnancy

On the onset hCG pregnancy administered to prevent miscarriage or pregnancy fading.

The indications for this are:

Risk of miscarriage.
A sharp drop in hormone levels.

The level of hCG is checked in dynamics, since low rates can be in the early stages, then they increase.

Important! Before the injection, it is necessary to conduct an ultrasound to exclude an ectopic pregnancy.

If the pregnancy is uterine, then to preserve it, 10,000 units of the drug are first administered, then twice a week, 5000 units each. Treatment can last from 8 to 14 weeks, depending on the patient's condition and hormonal levels. At the same time, Duphaston is prescribed to maintain progesterone levels.

How long does it take to ovulate

Usually ovulation comes in 24-36 hours after hormone administration. At this time, for the onset of pregnancy, sexual intercourse must occur every day.

Ovulation does not always occur after an injection, sometimes the corpus luteum continues to grow and turns into a cyst. Also, stimulation does not guarantee the onset of one's own ovulation in the following months.

Thus, an injection of hCG - this is a one time stimulation procedure rather than infertility treatment.

When to do the test

Hormone level grows in the first day the injection field, so ovulation tests are pointless to carry out within three days, as they will be false positive.

Checking for ovulation in 3 days after the procedure.

When to test for hCG levels

At the onset of pregnancy, the level HCG starts to rise. A strong decrease (by 20%) indicates serious problems:

Risk of miscarriage.
Ectopic pregnancy.
Delayed fetal development.
placental insufficiency.

To identify these pathologies before the beginning hormonal treatment ultrasound is required.

Normally, the level of the hormone constantly rises up to 11 weeks, then gradually decreases and remains unchanged throughout the entire period of bearing a child. For accurate diagnosis, it is necessary to take repeated tests in the same laboratory.

HCG norms in honey / ml:

Non-pregnant - 0-5.
1-2 weeks - 25-155.
3-4 weeks - 150-4800.
4-5 weeks - 2500-82000.
5-6 weeks - 23000-150000.
6-7 weeks - 30000-230000.
7-10 weeks - 21000-290000.
11-14 weeks - 6000-100000.
16-21 weeks - 4000-80000.
21-39 weeks - 2700-76000.

The first increase is fixed after 11 days of conception, the level doubles every 48 hours. At the level of 1000 units, a fetal egg is visualized during ultrasound. To confirm the normal course of pregnancy tests are done every two days. Indicators may be higher than normal with:

Multiple pregnancy.
Gestose.
diabetes mellitus.
Down Syndrome.

It may also indicate an incorrect determination of the gestational age.

Before donating blood for a hormone, certain conditions must be observed:

Take the test at the same time.
Do not drink alcohol and do not smoke.
Stop taking medication.
Avoid physical activity.
For several hours you should not take food and liquids, except for water.

Possible Complications

Hormone injection - it is interference with natural processes organism. Therefore, the following often occurs side effects:

Ovarian cyst.
vein thrombosis.
Ascites (accumulation of fluid in the abdominal cavity).
Hyperstimulation syndrome, in which there is a violation of breathing, palpitations, abdominal pain, dropsy.

Individual reactions can also be observed in the form of nausea, vomiting, indigestion, pain in the lower abdomen and lower back, mood swings, and depression. These symptoms disappear after the end of treatment.

Important! Hyperstimulation syndrome requires urgent medical attention and is treated in a hospital.

The hCG shot is essential ovulation support and subsequent pregnancy. It is prescribed if a woman does not produce enough hormone for any reason.

dosage and the scheme of application is chosen by the doctor, depending on the goals, the state of health of the woman. Usually pregnancy after such stimulation occurs in the first two months. It should be remembered that an hCG injection is not a means of treating infertility, but a one-time stimulation.

You may find the following video helpful:

Source: https://mirmamy.net/planirovanie/ovulyaciya/ukol-hgch.html

HCG shot to stimulate ovulation. Chorionic gonadotropin for men

The hCG hormone plays an important role in the human body. It is responsible for the reproductive function of the female and male genital organs, and also supports the development of the fetus in the womb. The lack of this hormone affects the ability of women to conceive, so gynecologists in such cases prescribe an injection of hCG.

Preparations containing hCG

Preparations, which include human chorionic gonadotropin, are used to treat men and women. The active substance can be obtained in several ways. Most manufacturers extract it from the urine of pregnant women, but some synthesize a specific protein using recombinant DNA.

There are many drugs containing hCG or its synthetic analogues, for example, Humegon, Pregnil, Ovitrelle. Doctors sometimes prescribe additional drugs for the treatment of infertility: Diferelin, Luveris, Duphaston, etc.

Release form and composition of chorionic gonadotropin

Chorionic gonadotropin is available in the form of a special powder, from which a solution for intramuscular injection is made. The powder is obtained by lyophilization - vacuum drying of biological material. This allows you to significantly extend its shelf life. The drug is packaged in sealed glass ampoules or vials.

They are placed in plastic or cardboard cells of 5 or 10 pieces. The package should also contain ampoules with a solvent - a solution of sodium chloride at a concentration of 0.9%. They need to dilute the powder until completely dissolved.

In addition to the main component, the composition of the drug also includes mannitol, which prevents clumping of the dry matter and promotes its uniform dissolution. It is a neutral component.

More often in pharmacies you can find chorionic gonadotropin 1500 IU, but there are other dosage options:

1000;
3000;
5000;
10000.

The concentration of the drug is selected individually based on the diagnosis and prescription of the attending physician. The composition of the drug from different manufacturers may vary slightly, all this is indicated in the package leaflet, the price may also differ. Store the drug in a cool place without direct sunlight.

Gonadotropin shot

Intramuscular injections of the drug are prescribed for various deviations in work reproductive system. Throughout the entire period of therapy, the patient is under observation and passes control tests.

Purpose and indications for hCG injections

The drug is prescribed for the treatment of infertility in women and men, as well as to maintain the natural level of the hormone in the body during pregnancy. Depending on the purpose, the injection scheme varies, as well as the duration of the course.

There are a number of indications for which the administration of gonadotropin is prescribed:

Stimulation of ovulation. In the event that a woman has problems with the development of eggs, injections of the drug help this process to proceed more actively. True, the likelihood of an ectopic pregnancy increases.
Reducing the risk of cyst growth. The hormone prevents the follicle from shrinking and forming a benign tumor inside the ovaries. Normally, the follicle bursts, and the cyst does not develop.
Maintenance of the corpus luteum at the initial stage of pregnancy. Due to hormonal imbalance, it can flake off and provoke a miscarriage.
Conducting artificial insemination and preparing the reproductive system of a woman for the transfer of embryos into the uterine cavity. In the process of such ovulation, not one follicle is obtained, but several at once.
Avoiding the risk of miscarriage early term if you already had a negative experience before.
Availability hydatidiform mole during previous pregnancies.

Such injections help not only to conceive a child, but also to endure it. With a correctly calculated dosage, it is possible to treat infertility in women with hormonal imbalance.

Stimulation of ovulation

An injection of hCG when stimulating ovulation is used if it cannot pass naturally. The causes of the problem are different, but the most common are tumor formations, the use of drugs that suppress reproductive function, and polycystic ovaries.

Injections are prescribed only on the basis of deciphering the data obtained from the results of tests for the level of hormones in the body.

Ultrasound of the pelvic area, as well as a table of measurements basal body temperature the patient plays an important role. The drug stimulates the onset of the ovulation period, regardless of what happens next with a mature egg.

She will either be fertilized naturally, or will be withdrawn for the IVF cryoprotocol.

Hormone treatment begins from the first day of menstruation, and if the cycle is knocked down, then from the first expected day of menstruation. It is worth considering the fact that oral contraceptives should be canceled no later than 5-7 days before the start of therapy.

During the stimulation of ovulation, you can not drink alcohol, drugs, it is not recommended to smoke. This can negatively affect the reproductive processes in the body. Worth limiting physical exercise, as well as protect a woman from stress and worries. It is recommended to avoid sex during this period.

Sexual intercourse will be effective only 5 days after ovulation.

When is testing done after an hCG injection?

After a woman has been given an injection of gonadotropin to stimulate ovulation, at least 3 days must pass before the release of the egg from the follicle. Sometimes it takes a little over 24 hours. At the same time, increased production of progesterone begins.

Depending on the length of the cycle, ovulation tests after the hCG injection begin to be done:

17 days before the onset of menstruation, if the length of the cycle is known and constant.
15 days before the start of menstruation, if the length of the cycle is not constant. To calculate the day, take the shortest cycle in the last 6 months.

Every day after diagnosing the growth of the follicle using ultrasound. This option is appropriate if there are long delays and breaks in cycles.

There is a huge variety of tests that differ not only in cost, but also in sensitivity. It is better to choose which test to use with your doctor.

Contraindications for HCG injection

Like any hormonal drug, chorionic gonadotropin injections have some contraindications. They are more associated with tumor neoplasms, as well as some individual characteristics organism.

Injections are contraindicated in the presence of any inflammatory processes associated with the reproductive system. This applies to both women and men.

You can not inject the drug if there is a pituitary tumor, as well as malignant neoplasms in the ovaries.

Because of this, deviations in the development of the genital organs of the child may appear. If there is suspicion or an established diagnosis of obstruction of the fallopian tubes, the doctor does not prescribe hCG injections.

Do not use the drug for thrombophlebitis and chronic inflammatory processes in the adrenal glands.

Instructions for use

Regardless of the diagnosis, gonadotropin is prescribed intramuscularly. When planning pregnancy before using the drug, it is recommended to undergo a complete examination. When stimulating the ovulation process, one-time injections are used with a dosage of 5000 to 10000 IU.

If there is a need to maintain the corpus luteum, then the drug is administered on the 3rd, 6th and 9th day after the onset of ovulation, the dosage is 1500-5000 IU.

Stimulation of superovulation for egg collection for IVF is also carried out using gonadotropin injections. For this, 10,000 IU are administered once. After 34-36 hours, the eggs are removed for their further fertilization.

This is done in the case when a woman cannot become pregnant on her own. If there is a possibility of spontaneous abortion, and symptoms appear no later than 8 weeks, the woman is injected with 10,000 IU on the first day and then 2 times a week for 5000 IU. Therapy continues up to 14 weeks.

If a woman’s previous pregnancy was interrupted due to a lack of the hCG hormone in the body, then when diagnosing a subsequent one, the same dosage is prescribed as a prevention of miscarriage as in case of a threatened miscarriage.

When diagnosing delayed sexual development, boys are prescribed from 3000 to 5000 IU once every 7 days. The duration of the course is at least 3 months, after which, if necessary, repetition is possible. Men are injected with 500-2000 IU 2 times a week. The duration of therapy is 1.5–2 months.

If idiopathic normohormonal oligospermia occurs, then it is treated with a weekly injection of 5000 IU of gonadotropin in combination with menotropin (menopausal gonadotropin). The course lasts 12 weeks. If the disease has developed due to androgen deficiency, 2500 units of the hormone are injected every 5 days for 3 months.

Gonadotropin preparations may cause some side effects. Most often they occur with an overdose. Women may show signs of ovarian hyperstimulation and a significant increase in their size. At this time, the chest and lower abdomen may also hurt.

In case of allergic reactions, redness may appear at the injection site, as well as a feeling of itching and pain. The general condition and well-being of the patient may deteriorate significantly. The drug is excreted by the kidneys, so attempts to check for pregnancy using test strips do not give the correct result.

An increased concentration in non-pregnant women can be observed for another 36-45 hours after the last injection.

Chorionic gonadotropin for men

Chorionic gonadotropin is used to treat diseases of the reproductive system in men. In addition, the drug is used by athletes.

If the functionality of the testicles in boys is assessed in the diagnosis of cryptorchidism or anarchism, an injection of 5000 IU is practiced once. For the treatment of cryptorchidism, gonadotropin is used at a dosage of 500–1000 units if the patient is less than 6 years old.

The drug is injected 2 times a week for 1.5 months. For children over 6 years of age and adults, this dosage increases to 1500 IU.

Athletes often use testosterone and its analogues in bodybuilding to obtain high sports results. As a result, testicular atrophy occurs. Gonadotropin is able to prevent this problem.

If you replace injections with a drug in tablets, this will not have the desired effect, although many manufacturers claim otherwise.

Most often, hCG is needed if an athlete starts taking Trenbolone, a very strong steroid for gaining muscle mass. Previously, it was used only in veterinary medicine. PCT (post cycle therapy) in this case is a prerequisite for maintaining the reproductive function of the genital organs.

With an overdose of the drug in men, there is an increase in the sensitivity of the nipples, gynecomastia, as well as an increase in the size of the inguinal testicles. Prolonged excess dosage also has negative consequences. It causes a sharp decrease in the number of active viable spermatozoa in semen.

Hormonal preparations based on gonadotropin have good feedback patients who have been treated for infertility or have used medication to maintain a pregnancy.

Carrying a pregnancy without human chorionic gonadotropin is impossible. In our article, we will analyze the role of this hormone in the onset of pregnancy and the principle of its action.

Purpose of hCG injections

In case of violation of the natural interaction of hormones in the female body, the process of follicle growth or the release of an egg may be disrupted or even absent. In such cases, after a complete examination and establishing the cause of the problem that has occurred, an ovulation stimulation scheme is selected, in which an injection of hCG 10,000 plays a significant role in starting this process.

HCG is the pregnancy hormone. In its natural state, the placenta begins its production from the moment of its formation and continues until childbirth.

He is also able to help the release of the egg from the ovary and support the work of the corpus luteum, which produces progesterone until the placenta is formed, which then continues this process throughout the pregnancy.

When is HCG prescribed?

An injection of hCG 10,000 is prescribed when ovulation does not occur (to start it). Previously, the entire first phase, according to the scheme selected by the doctor, estrogen substitutes stimulate the growth of the follicle to the desired size. It is controlled by ultrasound. This study first occurs a couple of days after the hormone course and continues at the same interval until the doctor records that the liquid bubble has reached 20-25 mm in diameter. At this point, the drug is injected. The injection is given 2-3 days after the last dose of the stimulant.

Ovulation after an injection of hCG 10,000 occurs after 24-36 hours. With a planned pregnancy, this period of time, plus one more day, is the most favorable for conception. Therefore, sexual intercourse is necessary on the day of the injection and the next two days.

The moment of cell release can be determined using urine tests. They begin to be carried out from the day obtained by subtracting the number 17 from the length of the regular menstrual cycle. If the cyclicity is broken, then 17 is subtracted from its smallest duration.

It is not recommended to use tests after an injection of hCG 10000, because to get exact result will not work. AT this case, to confirm the fact of cell release, it is better to conduct an ultrasound scan.

Types of hCG

Get this drug from the urine of women bearing children. It is sold in ampoules with a solution in doses of 500, 1000, 1500, 5000 and 10000 units. Names can be different:

chorionic gonadotropin;
rotten;
horagon;
ecostimulin.

HCG price

The cost is different everywhere. It depends on trademark, dosage and packaging volume (number of ampoules). The price of an injection of hCG 10,000 is an average of 1000-1500 rubles.

It should be remembered that the purchase of this drug is possible strictly by prescription. Only he decides what dose of the drug and at what time will bring desired effect.

So, an injection of hCG performs the following functions:

maintaining the growth of the corpus luteum until the placenta produces progesterone;
assistance in the formation of the placenta itself;
ovulation stimulation and corpus luteum support.

How much is an hCG injection

Many are interested in the question of how much an injection of hCG 10,000 comes out. It is difficult to give an answer to it. Each female body reacts differently to medications, the withdrawal period is different for everyone. Only a blood test for this hormone can confirm its current level.

At the onset of pregnancy, how much an injection of hCG 10,000 is excreted is generally difficult to say, since the developing placenta itself begins to produce it. The conducted analytics in this case shows an ever-increasing value. So, where the action of the injection ended, and the work of natural gonadotropin began, is almost impossible to determine.

Other uses of HCG

HCG is used not only in the absence of ovulation, but also in other cases:

to maintain the function of the corpus luteum;
with a habitual miscarriage;
the threat of miscarriage;
in violation of the menstrual cycle;
to prepare for IVF.

If this injection is prescribed, you need to know in what cases it cannot be used. Treatment is contraindicated:

with cancer of the female genital organs;
individual intolerance;
with some diseases of the thyroid gland;
early menopause;
tendency to blood clots;
with obstruction of the fallopian tubes;
during breastfeeding.

When will the pregnancy

The medicine fulfilled its role, the egg was released from the ovary and moved to fallopian tube to meet sperm. In anticipation of fertilization, the drug continues its action, supporting the corpus luteum, helping it produce progesterone, which is necessary for the completion of conception and the preparation of the uterus for the adoption of the ovum.

Pregnancy after an injection of hCG 10,000 occurs approximately 7 days after ovulation. This period of time is necessary for the embryo to descend into the uterus and attach to the endometrium. The placenta is immediately formed, which itself begins to produce chorionic gonadotropin, because its content increases.

Although a woman really wants to confirm this happy moment as soon as possible, it is not worth doing a pregnancy test after an injection of hCG 10,000 ahead of time. A high content of the drug can distort the result.

And even the fact that pregnancy occurs a week after ovulation will not show the full picture if you test on the 10th day after the injection of hCG 10,000. Due to its high content in the blood, you can get a false positive result.

It is also too early to start testing on the 12th day after the injection of hCG 10,000. You need to wait 1-2 weeks. But if you can't wait to confirm a fait accompli, you can take a blood test. With a frequency of every two days, growth dynamics is observed. If the indicators steadily increase, this will be confirmation of the successful development of the embryo.

In any case, when prescribing an injection of hCG 10,000, when doing pregnancy tests, the doctor decides who develops the regimen and treatment individually, adjusting to the characteristics female body and all survey data.

Chorionic gonadotropin is pharmacological agent and belongs to the group of hormonal agents. Most often it is known as the pregnancy hormone. After a successful conception, this hormone begins to be intensely secreted. Determining the level of hCG is one of the accurate diagnostic methods.

The topic, which is chorionic gonadotropin, does not lose its relevance today. This hormone is actively used to stimulate ovulation, that is, the release of an egg from the ovary into the fallopian tube, due to the bursting of the follicle. It is used in both sexes for medical reasons. What problems are solved thanks to this hormone and what effect it has on the body - this will be discussed in more detail in the article.

Release form and composition

The main component of the drug is human chorionic gonadotropin, which is produced by the human placenta and excreted in the urine of pregnant women.

The tool consists of:

White powder for intramuscular injection. The drug is available in vials containing 500ME, 1000ME, 1500ME and 5000ME - units of action. Additionally added to the composition of the substance mannitol.
As a solvent, a 0.9% physiological sodium chloride solution is used in an amount of 1 ml. The product is released in 5 bottles in a paper box.

The action of the drug

When ingested, the drug has the following therapeutic effect:

Among women:

normalizes the work of the ovaries;
increases the biosynthesis of sex hormones ─ progesterone and estrogen;
participates in the development of the placenta;
participates in the process of ovulation;
at the beginning of pregnancy stimulates the corpus luteum to produce progesterone.

For men:

participates in the formation of male germ cells - spermatozoa;
stimulates the production and disruption of the biosynthesis of steroid hormones;
promotes the formation of secondary sexual characteristics.

Pharmacokinetics

Chorionic gonadotropin after ingestion is absorbed well and then excreted within 8 hours by the kidneys. With daily use, accumulation of the drug is observed. The maximum concentration in the blood occurs from 4 to 12 hours.

Advantages and disadvantages of the drug:

despite the fact that the remedy is used for infertility and impaired impotence, scientists have proven that human chorionic gonadotropin can be used in weight loss, as it allows you to reduce the fat layer;
in some cases, the analysis of this hormone can detect tumors several months before the onset of symptoms. This helps to start the fight against the disease earlier and increase the effectiveness of treatment.

Indications for the use of Gonadotropin

The tool is used in the treatment of both men and women.

infertility in women associated with impaired ovarian function ─ a violation of the process of release of the egg from the ovary;
late sexual development of boys and girls, violation of the biosynthesis of the gonads, due to damage to the pituitary gland and hypothalamus;
habitual miscarriage or the inability of a woman to bear a fetus;
spontaneous miscarriage.

For boys and men:

delayed sexual development associated with dysfunction of the pituitary gland;
congenital underdevelopment or decrease in the functions of the sex glands and genital organs;
a disease associated with a decrease in the functions of the sex glands, obesity and underdevelopment of the genital organs;
testicular hypoplasia - the disease is an underdevelopment of one of the male gonads;
congenital pathology, which is associated with the absence of testicles in the scrotum;
a disease characterized by a violation of the biosynthesis of sex hormones: androgens;
a pathological condition with sexual underdevelopment, in which there is a deposition of fat in the shoulder girdle, on the abdomen, buttocks and thighs. It occurs during childhood.

Medication use and dosage

Instructions for use HCG:

The drug is prescribed to inject into the gluteal muscle, that is, intramuscularly. HCG injection is prescribed by the doctor for a course for a long period. It is important that this is done by a specially trained person who knows how to give intramuscular injections, or by a nurse in the treatment room.

The dosage and course of therapy is adjusted by the doctor individually depending on the disease.

The medication is available in the following dosages:

Chorionic gonadotropin 500 IU;
Chorionic gonadotropin 1 thousand units;
Chorionic gonadotropin 5000 IU;
Chorionic gonadotropin 1500 IU;
Chorionic gonadotropin 10000 IU.

The duration of therapy is 45 days, but there are some peculiarities.

The purpose of the remedy depending on the specific disease:

An injection of hCG when stimulating ovulation is done 1 time at a dosage of 10,000 IU.
If there is a threat of miscarriage, 10 thousand IU is administered once, then 5000 IU twice a week.
In case of ovarian dysfunction and elevated level estrogen - the dosage is 3000 IU at intervals of several days and the introduction of 2-3 injections on the 10-12th day of the menstrual cycle.
For regular production of the corpus luteum, they are injected on the 3rd, 6th, 9th day after ovulation hCG 5000 units
The drug is prescribed for boys in the absence of testicles in the scrotum with a course of 1.5 months, 2 times a week and a dosage of 1000 IU
Men are prescribed treatment with the drug for 30 days, 3 times a week at a dosage of 3000 IU. The new course is continued with a break after 6 weeks. During the year, such a course can be held three times.

How to dilute the drug Gonadotropin?

Before injecting the drug, you need to properly dilute it. It is recommended to use a freshly prepared solution before giving an injection:

without opening the bottle, remove the plastic cap and wipe it with alcohol;
measure with a syringe the required amount of solvent indicated in the instructions and pour it into the vial with the powder;
the diluted preparation should not be shaken vigorously, as its effectiveness may be reduced.

How to inject Gonadotropin?

An injection of hCG when stimulating ovulation is recommended by specialists in the abdomen, as it is much more convenient and less painful. This simple procedure can be mastered and done by yourself at home:

Procedure technique:

before injecting, wash your hands;
combine and gently mix the powder and solvent in one vial;
draw medicine into the syringe and choose the injection site, at the level or under the navel, stepping back 2 fingers;
wipe the abdominal area with an alcohol wipe;
grasping a fold of skin, insert the needle directly at an angle of 90 or 45 degrees and slowly pour in the medicine;
Remove the needle and wipe the injection site with an alcohol wipe.

How long does it take to get an hCG injection?

Firstly, there is no single answer to this question, since each organism is individual and the elimination period is different for everyone. The only way to confirm hormone levels is through a blood test.

Secondly, an injection of hCG 10,000 when it leaves the body during pregnancy is difficult to say, since natural gonadotropin begins to work.

Side effects

Self-treatment will lead to serious consequences:

allergy to the components of the drug;
women develop an increase in ovarian activity, which can lead to the formation of cysts, with the possibility of their rupture.
development of multiple pregnancy;
in men and boys, there is an increase in the mammary glands, possibly an increase in the prostate gland, skin rashes in the form of acne, earlier puberty.

Contraindications

The medication is contraindicated in case of:

Hypersensitivity to components.
The presence of a tumor in the genitals and breasts.
Disease of the veins, when a blood clot forms in the lumen of the vessel.
High blood pressure.
Lack of thyroid hormone.
Headache.
Sudden onset of seizures.

For women:

lactation period.
Incorrect formation of the genital organs.
Bleeding of unknown origin.
Obesity is an increase in body weight.

Features of use

The solution for injection is used freshly prepared, as it is prepared before each procedure. With prolonged storage, the effectiveness of the drug decreases.
There may be an increase in the size of the ovaries.
Do not use the product after the expiration date.
With prolonged treatment, antibodies to the drug are formed.
You should refrain from driving a vehicle until the end of the course.
Gonadotropin treatment for children under 3 years of age is not prescribed.

Overdose

With an overdose in women, the ovaries increase in size.

Price

The average cost of the drug Chorionic gonadotropin, depending on the dosage:

500 IU N5 powder and solvent ─ 415.30 rubles.
1500 IU N5 ─ 1087.80 rubles.
5000 IU N5 ─ 2652.50 rubles.

Terms of sale

Release from pharmacies only by prescription with indication of dosage.

Terms and conditions of storage

The expiration date depends on the dosage of the drug.

Chorionic gonadotropin 1500 IU, 1000 and 500 shelf life is 4 years, at a dosage of 5000 IU - 3 years.

Stored in a place protected from light room temperature not more than + 20 ° С and out of the reach of children.

Gonadotropin analogs

Sometimes the medication prescribed by the doctor is not suitable for the patient. Analogues of the drug come to the rescue:

Chorale;
Ecostimulin;
Horagon;
Pregnyl.

Stimulation of ovulation

In the absence of ovulation, women who are planning a child need help with conception. In this situation, artificial hCG preparations come to the rescue - special injections containing a remedy such as human chorionic gonadotropin.

An injection of hCG when stimulating ovulation is considered a safe and effective remedy.

So, an hCG injection for ovulation is prescribed by a specialist after a thorough examination of patients ─ testing for hormones, semen analysis - in men, which shows the ability to conceive and a compatibility test - in partners.

An injection of hCG when stimulating ovulation is prescribed:

In the absence of ovulation, due to hormonal imbalance or other elementary reasons, such as stress.
Habitual miscarriage. HCG injections are prescribed starting from the preparation stage, and during gestation.
Insufficient production of the corpus luteum, formed after ovulation, and producing the hormone progesterone. In this case, the course of injections is prescribed before the formation of the placenta.
In preparation for in vitro fertilization.
To improve the quality of sperm and increase the possibility of conception.

HCG injections during ovulation stimulation with clostilbegit

The drug Klostilbegit is used as a stimulant in which the formation of one or more eggs occurs. At the same time, the drug leads to an increase in the production of the hormone prolactin. The therapy is carried out under the control of ultrasound from the 5th -9th day of the cycle. Based on the examination, the dynamics of follicle growth is assessed to the desired size. When ovulation occurs, an hCG injection is prescribed to activate the process.

If after 3 stimulations there was no progress in treatment, it is worth resorting to other therapy regimens. At misapplication possible early menopause.

Unfortunately, ovulation after an hCG injection is not always successful. A reduced level of hCG can cause fetal death, missed and ectopic pregnancy.

Contraindications for stimulation:

Infectious diseases;
Inflammatory processes;
Hormone imbalance;
Inflammatory diseases of the liver;
Obstruction of the fallopian tubes;
male infertility;
Poor semen analysis.

It is important to remember that self-treatment with hormones is unacceptable, this can affect the state of the body. In this regard, taking the drug chorionic gonadotropin and its analogues should be taken under the strict supervision of a specialist and monitor the hormonal background and the general condition of the patient. This will greatly increase the chances of recovery.

chorionic gonadotropin reviews in women with stimulation:

Elsa, Yekaterinburg

There were problems with ovulation, the follicles developed, but did not burst. The gynecologist prescribed an injection of hCG 5000 IU in one of the cycles. The doctor monitored the development of the follicle by ultrasound and gave injections. Everything went well. The long-awaited pregnancy has come. With an injection, the chances of conception increase.

The only drawback is the price of the issue.

Alena, Petrozavodsk

For a long time it was not possible to get pregnant, as there were hormonal problems. There was no need for stimulation. The gynecologist ordered a series of tests and prescribed a course of drugs. Among them was Gonadotropin 1000 IU. Thanks to this tool, I was able to conceive the first time.

I am grateful to the drug for the happiness of motherhood.

Varvara, Murom

My husband and I wanted a second child, but there was a frozen pregnancy at an early stage. The doctor said that the problem is the presence of endometriosis. After undergoing a course of treatment to improve the inner layer of the uterus, the result was obtained, and the gynecologist gave the go-ahead for conception. To enhance ovulation, he recommended an injection of hCG 5000 IU. The ultrasound doctor confirmed the presence of ovulation. Everything worked out, thanks to the medicine for a real chance!

Chorionic gonadotropin: general information

HCG or human chorionic gonadotropin has two subunits in its structure: alpha and beta. The alpha subunit is structurally identical to the TSH, FSH, and LH subunits. The beta subunit has no analogues. It is she who is the basis of tests that determine pregnancy.

The production of the beta component of hCG occurs in the first weeks of pregnancy. And by the 11th week, its content grows thousands of times. After that, its level begins to gradually fall. For this reason, it is important to monitor human chorionic gonadotropin during the perinatal period. So the control of the hormone level allows you to timely determine its decrease or increase, which may indicate the development of certain pathologies of pregnancy (threat of interruption, ectopic pregnancy and etc.).

In addition, a woman registered for infertility must undergo an examination to detect antibodies to hCG. These antibodies do not allow the protein to function fully, which leads to a decrease in placental lacogen, estradiol, and progesterone. Due to chorionic gonadotropin, the rejection of the embryo, its death inside the mother's womb, is excluded. This is another argument in favor of monitoring its level. Patients who have antibodies to hCG in the blood are recommended to perform plasmapheresis and take advantage of the possibilities of in vitro fertilization.

Usually, the level of chorionic gonadotropin is monitored during pregnancy, which is normal in such a situation. However, testing for beta-CHG in some cases may be indicated for some non-pregnant women and even men. An analysis that detects chorionic gonadotropin in the blood is prescribed for men and non-pregnant women when it is necessary to confirm hormone-producing tumors.

For injection, chorionic gonadotropin is produced in the form of a solution or in the form of a lyophilisate (a solution is prepared from it). This protein is harvested for production hormonal drugs from the urine of pregnant women.

Indications for the use of hCG injections

The effectiveness of drugs with hCG was noted when the following conditions occur in women:

dysmenorrhea;
ovarian dysfunction;
anovulatory infertility;
corpus luteum deficiency;
the threat of spontaneous miscarriage;
inability to bear fruit;
preparation for IVF;
placenta formation.

The drug with hCG can act as an additional tool for assisted reproductive techniques.

Recombinant hCG affects:

on the ovaries and tissues to enhance the production of sex hormones;
when stimulating ovulation.

Instructions for the use of HCG

The drugs are injected intramuscularly. It is permissible for a woman to inject herself with hCG, but only if she knows how to make intramuscular injections. Otherwise, she will have to look for a person from her inner circle who could do it for her. If none of the options is possible, then you can go for injections to the treatment room of the antenatal clinic that the patient visits at the place of registration. But this option is not entirely convenient, since injections are prescribed for a long time, in whole courses, and the opportunity to visit the treatment room of the clinic is not always possible. Therefore, it is best to still find a person who can come to the house or do it yourself.

When stimulating ovulation, the doctor will recommend an injection of hCG into the stomach. It is much more painless and more convenient than when placing it in the buttock. To do this, measure the distance of about two fingers from the navel to the left and right. Having pinched the fold of the skin, the needle is inserted into it to the end. The needle for these purposes is better to choose a short, insulin. The injection site must be treated with a cotton swab dipped in an alcohol solution.

Permissible doses of drugs with HCG.

The volumes of chorionic gonadotropin may be different. The following dosages of the hormone are found in the pharmacy network: 500 units, 1000 units, 1500 units, 5000 units, 10000 units.

Dosages for various problems obstetrician-gynecologist can prescribe the following.

The dosage of injections of chorionic gonadotropin, which is prescribed to maintain pregnancy, can be from 5000 IU to 10000 IU. Each time it will depend on how much of the hormone was detected in the blood of the pregnant woman. In addition, the size of the follicle is taken into account, since due to the injection of the drug with hCG, ovarian hyperstimulation syndrome may develop.

One of the main indications for the use of hCG injections is infertility. After ovulation stimulation, several ultrasound examination procedures are prescribed. At ultrasound sessions, follicle growth is monitored (up to 20-25 cm) and then hCG is injected, which triggers the ovulation mechanism. Also, the action of the hormone is directed against the regression of the follicles, that is, it prevents the development of a follicular cyst. In order to stimulate ovulation, chorionic gonadotropin is indicated once at a dose of 5000 or 10000 units. Evaluate the effect of the injected injection after 24-36 hours using ultrasound equipment. Performing injections with hCG increases the possibility of conception many times over.

To stimulate the performance of the corpus luteum for 3-6-9 days, chorionic gonadotropin is indicated at a dose of 1500 units or CG 5000 units.

When performing superovulation as part of reproductive measures, the patient, after stimulating the growth of several follicles, is injected once with about 10,000 units of chorionic gonadotropin. The selection of the egg is carried out after 34-36 hours from the moment of CG injection.

If a threatened miscarriage is suspected, 10,000 units of the drug are first administered, after which the dose is reduced to 5,000 units, which is administered twice a week. Therapy is started before the 8th week of gestation, it can be continued up to the 14th week.

Indications for injection of hCG for pregnant women.

Pregnant women are prescribed injections with hCG with a sharp drop in the level of human chorionic gonadotropin in the blood in order to maintain pregnancy in the future. The low concentration of this complex protein in the blood may be due to early diagnosis. Before prescribing hormone therapy for a pregnant woman, the doctor will once again send for analysis to confirm the lack of gonadotropin.

In situations in which the deviations of the indicator are significant from the normal value, always taken into account for the week of pregnancy, and this deviation to the smaller side is more than 20%, then the course of hormone therapy is prescribed in without fail. Such a deviation in the hormone index may be evidence of anomalies, such as:

ectopic pregnancy;
frozen pregnancy;
chronic placental insufficiency;
risk of miscarriage.

Side effects of hCG shot

Side effects in women: due to the administration of the drug, ovarian hyperstimulation syndrome, hydrothorax, ascites, thromboembolism, and cysts may occur.

Other side effects from hCG are rare. It can be discomfort and a feeling of pulling pain in the abdomen, flatulence (gas formation in the abdomen), mood swings, excessive anxiety and fatigue. After the course of treatment is completed, such symptoms usually disappear.

List of contraindications.

Measures with the artificial administration of a hormone-containing drug are contraindicated:

during lactation;
at the onset of early menopause;
with a tumor process in the pituitary gland and ovaries;
with thrombophlebitis;
when the fallopian tubes are found to be impassable;
when allergic reactions for the drug
with diseases of the adrenal glands;
with hyperthyroidism.

If there are difficulties with conceiving or carrying an embryo, the doctor will first identify the cause of this violation by prescribing an hCG test and a number of other examinations. With all the importance of chorionic gonadotropin for the processes of ovulation and for maintaining the development of the fetus, as well as with its identified shortage and for some other indications, the doctor prescribes hCG injections to artificially restore the lost balance of the amount of the hormone in the woman's body.

At the same time, one should not worry that this hCG injection will be dangerous for the health of the woman herself or for the fetus.

In most situations, it is thanks to this measure that future mother It turns out to keep and endure a healthy baby. The sooner a medical emergency disorder is identified, the greater the chance of a positive outcome.