Candles from the fungus for women. Review of the best candles for thrush - advantages, disadvantages. Advantages and disadvantages of suppositories against fungus for women. Reviews

Special attention deserves a separate class - mushrooms. They are neither animals nor plants. Some of them are edible, others are poisonous, some heal, others maim.

Pathogenic fungi like to settle on the skin, nails, scalp, and reproductive organs. Many of them live with us in symbiosis and become dangerous in exceptional cases - with a decrease in immunity, oncological diseases, and a violation of the microflora.

Thrush - those women who have not encountered it can only be congratulated. And so - itching, redness, unpleasant discharge - these are typical manifestations of this disease. Even in ancient Greek medical treatises, you can find references to this disease.


What to do? Run to the doctor! Antifungal drugs in gynecology are used in various dosage forms.

Medicines to fight the fungus

The list of drugs for the treatment of fungal diseases is quite wide - from inexpensive, budgetary funds to rare expensive drugs. The release forms are also diverse - candles, tablets, ointments and creams.

So, let's go through the main medicines for the treatment of fungus:

Purpose, use and side effects

Modern drugs are able to cope with the fungus in 1-3 days. This distinguishes them favorably from the medicines used by our mothers and grandmothers. The same nystatin will need to be taken for more than a week.

Any medicines have contraindications and side effects. Therefore, they should be prescribed by a doctor after an examination.

Usually, systemic antifungal drugs are not prescribed to pregnant and lactating women. Tablets for oral use are prescribed in cases where local treatment has not given a positive result, in the chronic course of the disease.

Of the side effects, problems with the gastrointestinal tract most often appear, these are:

  • vomit;
  • nausea;
  • diarrhea;
  • occasionally taste disturbances.

Therefore, dear ladies, you should not independently prescribe one or another group of drugs for yourself. As well as the form of administration - tablets or suppositories. Only a gynecologist can assess the scale and correctly prescribe treatment.

Candles for thrush is the most convenient way to locally treat vaginal candidiasis in women. The action of vaginal suppositories is due to the deep penetration of the active antifungal substance into the mucous membrane, while the pathogen is destroyed, inflammation is eliminated, and the inflammation is reduced.

The pharmaceutical industry offers a wide range of different ones - these are both suppositories for local treatment and drugs for oral administration, which are prescribed by a doctor in severe forms of candidiasis, in the chronic course of thrush as part of complex therapy.

What candles from thrush are better? There is one answer to this question - these are the drugs to which the Candida fungus is sensitive according to the result of bacterial seeding and determining the resistance, resistance or sensitivity of the pathogen to a particular drug. Since in chronic, often relapsing, it may not be effective due to the development of drug resistance in fungal agents.

Uncontrolled, self-treatment of thrush leads both to the development of chronic candidiasis and to a violation of the vaginal microflora. Moreover, many women actively practice, which is not acceptable, as it only provokes further progression of the disease, further disrupting the vaginal microflora. Only the attending physician, based on the patient's history, clinical picture, taking into account the sensitivity of the pathogen, prescribes an adequate treatment regimen. Even with the disappearance of symptoms, clinical recovery is considered to be the absence of fungi according to laboratory data for the next 3 months.

Rules for the use of suppositories against thrush

In the absence of therapy from a permanent partner, a ping-pong effect occurs when a woman, after treatment, is again subjected to a fungal attack during unprotected intercourse.

During therapy, you should either refuse sexual intercourse or use condoms. Candles are inserted deep into the vagina at night to improve the absorption of the drug.

When a woman is diagnosed with vaginal candidiasis, she should be analyzed together with her doctor, because without eliminating or minimizing provoking factors, thrush can occur again and again.

Very often, candidiasis indicates the presence of other sexually transmitted infections (mycoplasmosis, gonorrhea, trichomoniasis, etc.) as well as the development of gardnerellosis ().

Depending on the intensity of the symptoms, acute or chronic process, the treatment may differ in the course of therapy, in some cases it is enough to use 1 suppository, and in the chronic course of the process this is not enough and longer treatment is required.

  • Vaginal suppositories cannot be used during menstruation, with the exception of Povidone-Iodine (Iodoxide, Betadine) and Sertaconazole (Zalain).
  • For 1 candle, you can use the following suppositories - Zalain, Lomexin
  • 3 candles each - Livarol, Gino-pevaril, Pimafucin.
  • 5-14 suppositories each - Macmirror, Clotrimazole, Ginezol, Yodoxide, Nystatin, Polygynax, Terzhinan, Irunin.

During treatment, you should not wear synthetic, tight underwear, you must follow all the rules of intimate hygiene, change towels and linen daily, do not use chemicalized, flavored pads, toilet paper, intimate hygiene liquids, which only worsen the condition.

The best candles for thrush - Livarol, Pimafucin, Zalain, Nystatin, Clotrimazole, Lomixin, Macmirror - the pros and cons of using

Sertaconazole - Zalain

Zalain(price 1 soup. 480-520 rubles, prices 2018)

It is a derivative of benzothiophene and imidazole.

Use in pregnancy: There is no sufficient data on the potential harm to the fetus and during the feeding period. But given the single method of application and the lack of systemic action of Zalain - during pregnancy, lactation, it is possible to use it in a situation where the intended benefit to the woman is higher than the possible risk to the child.
Contraindications: Hypersensitivity
Side effects: that do not require discontinuation of the drug, allergic reactions.
Mode of application: 1 suppository from thrush is inserted into the vagina at night once, if symptoms persist after a week, re-use is possible. Before use, wash the external genitalia with neutral soap. May be used during menstruation.
Advantages and disadvantages: The advantage of using Zalain from thrush is the one-time administration of the drug, high efficiency, the ability to use during menstruation, the disadvantage is the high price.

Ketoconazole - Livarol

  • Livarol (price 430 rubles for 5 pcs. 600-800 for 10 pcs.)
  • Ketoconazole 230-400 rubles.

Contraindications: hypersensitivity, 1st trimester of pregnancy, in the 2nd-3rd trimester with caution.
Side effects: irritation, redness of the vaginal mucosa, itching. Skin rash, urticaria.
Application: In the supine position, it is injected into the vagina deeply, 1 suppository for 3-5 days, with the chronic nature of thrush for 10 days.
Pros and cons: The advantage is the rapid effect, almost no allergic reactions. It is prescribed most often at the first time the diagnosis is established, with frequent or prolonged use, drug resistance occurs in the pathogen.

Itraconazole - Irunin

Irunin - vaginal tablets 10 pcs. 300-320 rub.

Contraindications: 1st trimester of pregnancy, in the 2nd-3rd trimester with caution, hypersensitivity, lactation
Side effects: itching, burning, skin rash that does not require discontinuation of the drug.
Application: at night for 7-14 days.
Pros and cons: An effective remedy for recurrent thrush and resistance to other antifungal agents, the disadvantage is that it cannot be used in the 1st trimester.

Nystatin + Nifuratel

(price 680 rubles for 8 pcs.)

Pregnancy: approved for use
Contraindications: hypersensitivity
Side effects: very rarely itching, skin rash
Application: Intravaginally, 1 suppository 8 days before bedtime.
Advantages and disadvantages: The main advantage in the possibility of therapy during pregnancy, the disadvantage is the high price.


  • (30-60 rubles 6 pcs),
  • Candide B6 (70 r), Antifungol, Kanesten,
  • Candizol, Yenamazol 100, Candibene.

Contraindications: hypersensitivity, it is strictly forbidden to use in the 1st trimester of pregnancy, while breastfeeding
Side effects: burning, itching, vaginal discharge, abdominal pain, headache, cystitis, frequent urination, pain during intercourse.
Mode of application: within 6 days, 1 suppository deep into the vagina at night.
Advantages and disadvantages: The advantage is that these are inexpensive suppositories against thrush, the disadvantage is frequent side effects, the rapid development of resistance in fungal agents.

Miconazole — Klion D, Neo-Penotran

Ginezol 7 (280-300 rubles), Gino-dactanol, Daktarin, Mikozon (cream).
Combined preparations, which include, in addition to miconazole, also metronidazole.

  • Klion-D 100 (price 330 rubles ..),
  • Neo-Penotran (14 pieces 700 rubles),
  • Metromicon-Neo (14 pieces 300-350 rubles)

Contraindications: hypersensitivity, with caution in pregnancy 2-3 trimester, lactation (suspend feeding during treatment) in diabetes mellitus, liver dysfunction, herpes
Side effects: only at the beginning of treatment, a feeling of discomfort, burning, itching, nausea, diarrhea, abdominal pain is possible.
Mode of application: within 6-7 days at night, 1 suppository., you can not take alcohol during treatment.
Pros and cons: quick effect, wide spectrum of activity, does not cause dysbacteriosis, effective for frequent recurrences of thrush, the disadvantage is the danger of using during childbearing and feeding.

Econazole

gyno-pevaril(3 pieces 420 rubles 15 pieces 800 rubles), Ifenek

Contraindications: hypersensitivity, pregnancy (1 tr.), since it penetrates into the systemic circulation, in 2-3 with caution, when feeding, breastfeeding should be stopped.
Side effects: local irritation, rash, itching.
Application: suppositories of 50 mg. within 14 days, even after the disappearance of symptoms, the course must be completed. Candles 150 mg. - within 3 days, if after 7 days the culture test gives a positive result, the course of treatment should be repeated.
Advantages and disadvantages: effective suppositories for thrush.

Natamycin - Pimafucin

Effect on the fetus: approved for use during pregnancy
Contraindications: increased individual sensitivity
Side effects: mild irritation
Mode of application: within 3-6 days, 1 suppository.
Advantages and disadvantages: the advantage of Pimafucin from thrush is the lack of effect on the fetus, so it is prescribed during pregnancy.

(30-60 rubles)
Complex preparations containing nystatin:

  • Polygynax (nystatin, neomycin, polymyxin B, price 6 pcs. 350 rubles, 12 pcs. 600 rubles),
  • Terzhinan (prednisolone, neomycin, ternidazole, nystatin - 6 pcs. 360 rubles, 10 pcs. 450 rubles), but their use is fraught with the development of dysbacteriosis.

Contraindications: pregnancy of any term, individual sensitivity
Side effects: chills, diarrhea, abdominal pain, vomiting, nausea
Mode of application: 2 r / day (morning and evening) for 10-14 days.
Pros and cons: The disadvantage of nystatin suppositories against candidiasis is a long course, use 2 times a day, the presence of serious side effects. The advantage is that they are cheap, candida does not develop resistance to nystatin, so it is often prescribed for chronic, recurrent candidiasis.

Povidone Iodine - Iodoxide

(10 pieces 300 rubles), Betadine(price 7 pieces 400 rubles, 14 pieces 500 rubles)

Contraindications: thyrotoxicosis, thyroid adenoma, with caution in renal failure, with individual sensitivity, during pregnancy is not recommended, contraindicated in the 1st trimester, in the 2nd-3rd trimester and during lactation - with caution.
Side effects: allergic manifestations, local hyperemia
Mode of application: In acute vaginitis 2 r / day for a week, 1 suppository, with chronic 1 r / day for 2 weeks, regardless of the phase of the menstrual cycle.
Pros and cons: the possibility of use during menstruation, is used in complex treatment for bacterial vaginosis.

Fenticonazole - Lomexin

(fenticonazole, price 1000 mg. 1 pc. 400 rub. 600 mg. 2 pcs. 600 rub)

Contraindications: pregnancy, can not be used during menstruation, with individual intolerance to the components of the suppository.
Side effects: mild symptoms of irritation that go away on their own and do not require discontinuation of the drug, allergic reactions - rash, urticaria, erythema
Mode of application: capsule 600 mg. are administered once, according to indications, if symptoms persist, it can be used for 3 days. Capsules 1000 mg. introduced within 2 days.
Advantages and disadvantages: effective remedy, can not be used during pregnancy.

Dequalinium chloride - Fluomizin

Fluomizin - vaginal tablets 6 pcs. 560 rub. - antiseptic in gynecology (bacterial vaginosis, candidal vaginitis, sanitation before childbirth and operations)

Contraindications: ulcerative lesions of the cervix and vagina, girls before the onset of sexual activity, pregnancy 1-2 trimester - there is no data on the safety of use
Side effects: symptoms of irritation, allergic reactions - rash, urticaria, erythema
Mode of application: capsule at night, for 6 days, stop treatment during menstruation, continue after.

In addition to suppositories, it is possible to use creams with antifungal drugs:

  • Clotrimazole - Candide (with an applicator 80 rubles), Clotrimazole cream 120 rubles, Canison 80 rubles.
  • Econazole - Ecodax cream 140 rubles
  • Isoconazole - Travogen cream 500-700 rubles.
  • Fenticonazole - Lomexin cream 600 rubles.
  • Butoconazole - Gynofort cream with applicator 600-700 rubles.

In chronic recurrent thrush, oral antifungal drugs are required:

  • Fluconazole 40-50 rubles (and more expensive analogues Flucostat, Mikomax, Mikosist, Diflucan)
  • Tinidazole 30-70 rub
  • Ketoconazole - Mycozoral 460 rubles
  • Itraconazole - Irunin 320 rubles, Itrazol 380 rubles, Orungamine.

After antifungal therapy, the doctor may prescribe drugs to normalize the vaginal microflora, that is, creating conditions for the growth of lactobacilli in the vagina:

  • Vagilak 2 r / day (candles with bifidobacteria) 5-10 days.
  • Laktozhinal, Atsilakt (lactobacilli) vaginal capsules for 1 to 10 days.
  • For oral administration - Bificol 10 days.

Advantages and disadvantages of using suppositories for thrush

Benefits of using topical preparations for candidiasis in women:

  • When the drug is injected into the site of active reproduction of fungi, the effect of local treatment appears much faster, especially when using modern effective drugs such as Livarol or Zalain.
  • Modern antifungal agents can be used once.
  • Since the systemic absorption of topical preparations is low, the incidence of side effects is reduced, in contrast to oral therapy.

Disadvantages of local treatment:

  • Local treatment gives a woman some inconvenience - soils underwear, limits her sexual life.
  • The positive effect of such therapy is possible only with mild forms of thrush, but when the course of the disease is more severe, prolonged, local therapy should be supplemented with the use of. Therefore, it is often necessary to repeat the course of treatment after a certain time.
  • When using combined antimicrobial drugs, such as Terzhinan, Polygynax, a common side effect is vaginal dysbacteriosis, which then requires additional treatment, for example, the use of suppositories with lactobacilli - Lactonorma, Acylact, Lactobacterin, Ecofemin or Vagiflora.

Candles from thrush during pregnancy

Very often in women during pregnancy, due to a physiological decrease in immunity, thrush occurs, and many drugs are either categorically impossible to use, or there have been no reliable safety studies for the fetus. Among the entire selection of local preparations, the following suppositories are approved for use:

  • Candles - Pimafucin, Primafungin (active ingredient Natamycin).
  • Combined drug - Macmirror complex (active ingredients Nystatin and Nifuratel).
  • In the 2-3 trimesters Clotrimazole, Nystatin (low efficacy) or the ancient Borax in glycerin (Sodium tetraborate in glycerin), Pimafucin, Gyno-Pevaril, Gynofort (vaginal cream), all of these drugs are used during pregnancy with caution if there is a potential risk maternal health outweighs the risk to the baby.

  • Some doctors prescribe a combination drug - Terzhinan (prednisolone, neomycin, ternidazole, nystatin), but the instructions for it indicate that from the 2nd trimester it can only be used when assessing the potential benefit to the mother and harm to the fetus, as it has undesirable side effects and contains a hormonal drug - prednisolone.

Candidiasis suppositories are a number of drugs that allow you to cure thrush in a short time. Consider the most effective candles for candidiasis, the principle of their action, the main indications and instructions for use.

The action of suppositories is based on the deep penetration of the active substance into the mucous membrane. Thanks to this, the pathogen is destroyed, inflammation and the general symptoms of candidiasis are reduced. To date, the pharmaceutical market has many different antifungal suppositories. Drugs differ in their effectiveness, cost, possible side effects and contraindications. There are suppositories that are effective in severe forms of candidiasis, and some are used to prevent thrush or are included in the therapeutic complex of the disease.

In order to choose really effective suppositories for candidiasis, you need the drug to which the fungus is sensitive. To do this, you need to see a doctor and take smears. According to the result of bacterial culture, the doctor determines the stability, resistance and sensitivity of the fungus to certain drugs. This is because with chronic thrush or often recurrent, treatment may not bring the desired results, as the fungus becomes resistant to the drug.

  • If candidiasis has just appeared or has a not too advanced form, then Livarol, Ginezol, Clotrimazole suppositories can be used for treatment. These drugs quickly and reliably relieve the symptoms of thrush without causing allergic reactions. In addition, candles have a preventive effect.
  • With advanced or chronic thrush, stronger suppositories are used for treatment. This category of drugs includes Ketoconazole and Nystatin. The advantage of these suppositories is that they are effective in treating the most advanced stages of candidiasis. But it is contraindicated to put such candles on your own. Since a strong therapeutic effect can cause vaginal dysbiosis. After such treatment, it will be necessary to restore the microflora with the help of another treatment.
  • Strong suppositories from thrush are prescribed with probiotics, that is, preparations containing beneficial bacteria to maintain the normal microflora of the body. In addition, candles with a pronounced therapeutic effect are contraindicated for pregnant women.
  • But vaginal suppositories Ovulum or Macmirror are used in combination with other suppositories, as they have an antiseptic effect. Thanks to this, it is possible to cure not only thrush, but also a number of other infections that provoke the disease.

, , , ,

Indications for the use of suppositories from candidiasis

Indications for the use of suppositories for candidiasis are based on the action of a particular drug. First of all, it should be noted that both partners need to be treated, since in men, thrush can be asymptomatic. Due to the lack of treatment in a man, in a woman, candidiasis becomes chronic and constantly recurs.

As a rule, candidiasis indicates the presence of sexually transmitted infections. The disease can lead to bacterial vaginosis and bacterial vaginosis. Depending on the manifestation of symptoms, chronic or acute process, therapy differs in the duration of treatment. For the treatment of candidiasis in some patients, one suppository is sufficient, but for chronic thrush in others, it is necessary to undergo a full course of treatment.

The main indications for the use of suppositories from candidiasis:

  • Treatment and prevention of diseases caused by Candida fungi.
  • Treatment of candidiasis of the mucous membranes and internal organs.
  • Prevention of the development of candidiasis with prolonged use of antibiotics, penicillin, oral drugs and tetracycline antibiotics.

Vaginal suppositories for candidiasis

Vaginal suppositories for candidiasis are effective medicines that allow you to quickly and effectively get rid of the symptoms of a fungal disease. But it is better to use vaginal suppositories after consultation and examination by a gynecologist. Since the doctor will prescribe the remedy that is safe for your body, it will cure thrush and will not have side effects.

For the treatment of candidiasis, the following vaginal suppositories are used:

  • Combined preparations of local action.
  • Antifungal drugs.
  • Antimicrobials for topical use.

If the treatment is carried out with antifungal drugs, then after therapy, the woman needs to restore the normal microflora of the vagina. Useful lactobacilli will protect against relapses of the disease and foreign microorganisms.

Some women are faced with the fact that the use of vaginal suppositories for candidiasis does not bring the desired result. There are several reasons for this phenomenon:

  • To some drugs, the disease becomes resistant, because of this, the treatment is not beneficial. Drug resistance may occur due to an incomplete course of treatment or a small dosage that did not kill the fungus and gave it the opportunity to adapt to the drug.
  • Incorrect self-treatment is another reason for the ineffectiveness of the candles used. Many women with thrush self-medicate. For this, therapeutic tampons and preparations for raising immunity can be used. But it is better to use proven drugs, that is, vaginal suppositories.

Vaginal suppositories differ in active ingredients, terms of treatment and therapeutic range. A number of drugs are forbidden to use during pregnancy and menstruation. For treatment, you need to choose such suppositories, the use of which will not cause a violation of the vaginal microflora, the drug will be effective not only for fungal, but also for mixed infections. Candles should not give complications in the form of allergic reactions, have a minimum of contraindications and side effects.

Rectal suppositories for candidiasis

Rectal suppositories for candidiasis can be used in case of intestinal fungal disease or vaginal thrush. Rectal suppositories are suitable for pregnant women and in the treatment of thrush during menstruation. Consider a few effective rectal suppositories for candidiasis.

  • Viferon

A complex drug with antiviral, antiproliferative and immunomodulatory effects. The drug is used to treat urogenital infections, infectious and inflammatory diseases, intrauterine infections. Suppositories are effective in the treatment of candidiasis, bacterial vaginosis, herpes infection, chlamydia, ureplasmosis and a number of other viral lesions.

Rectal suppositories are used as prescribed by a doctor. As a rule, for the treatment of candidiasis, patients are prescribed one suppository twice a day. The course of treatment takes from 5 to 14 days. In rare cases, Viferon causes allergic skin reactions that disappear 72 hours after discontinuation of the drug. Candles are contraindicated for individual intolerance to the active substance or components of the drug.

Viferon is allowed to be used to treat candidiasis in pregnant women, but only from the 14th week, but there are no contraindications when using suppositories during lactation. To date, cases of drug overdose have not been recorded. Candles are dispensed from pharmacies without medical permission.

  • Nystatin

A drug effective against pathogenic fungi, especially Candida fungi. Despite its effectiveness, the drug is poorly absorbed, so the bulk of the suppository is excreted in the feces. Nystatin is used to treat and prevent candidiasis of the mucous membranes of the vagina, mouth, skin, and internal organs. The drug is also effective in the prevention of candidiasis, especially with prolonged use of antibiotics, tetracycline drugs and penicillin.

Rectal suppositories are used twice a day, injected deep into the rectum. The duration of the course of treatment takes from 10 to 14 days. Nystatin has low toxicity, so it does not cause side effects. The drug is contraindicated in patients with individual sensitivity to the components of the drug, as this can cause nausea and vomiting, chills, fever. Rectal suppositories for candidiasis are used only as directed by a doctor.

  • Pimafucin

An antifungal drug with the active ingredient natamycin (macrolide antidiotic). The drug has a wide spectrum of action and is sensitive to fungi of the Candida genus. Rectal suppositories are prescribed for the treatment of fungal diseases of the gastrointestinal tract, vaginal candidiasis, vulvovaginal candidiasis. The drug is used in the complex therapy of fungal diseases.

Suppositories are placed at night, as a rule, one candle per day. The duration of treatment is determined individually for each patient, but on average the course of treatment lasts from 3 to 6 days. After the main treatment course, a prophylactic course is carried out, 3-4 days after the disappearance of the symptoms of candidiasis. Side effects of the drug are manifested in the form of itching and allergic reactions. Candles are contraindicated for hypersensitivity to the components of Pimafucin. The drug is contraindicated for the treatment of candidiasis in pregnant women.

Release form

The form of release of suppositories from candidiasis is vaginal and rectal suppositories. Candles differ in their shape and color. In addition, suppositories differ in the amount of active substance. Each candle is individually packaged for ease of storage and use. Thanks to the pointed end, suppositories are easily inserted both into the vagina and rectally.

The release form of suppositories for the treatment of candidiasis accelerates the healing process. This is due to the fact that the active ingredients of the drug act directly on the affected mucous membrane. For greater efficiency, before using suppositories, it is necessary to empty the bladder and intestines and only then introduce a suppository, and the deeper the better.

Pharmacodynamics of suppositories from candidiasis

Pharmacodynamics of suppositories from candidiasis are processes that occur with the active substance of the drug after its use. Consider the pharmacodynamics of suppositories for candidiasis using the example of Livarol intravaginal suppositories.

The active substance of the drug is ketoconazole. The substance is an antimycotic of the imidazoledioxolane group, it has a fungistatic and fungicidal effect. The drug is active against Candida yeast-like fungi, as well as Pityrosporum, Trichophyton spp., Streptococcus spp. and Staphylococcus spp.

Suppositories are used to treat acute and recurrent vaginal candidiasis and for its prevention in weakened immunity at the time of use of antibacterial drugs that disrupt the natural microflora of the vagina.

Pharmacokinetics of suppositories from candidiasis

The pharmacokinetics of suppositories from candidiasis are the processes of absorption, distribution, metabolism and excretion of the drug after use. Consider the pharmacokinetics on the example of Pimafucin suppositories. Suppositories are intended for intravaginal administration, dissolve quickly at body temperature. Candles form a voluminous foamy mass, which evenly distributes the active substance along the walls of the vagina.

The composition of the drug includes cetyl alcohol, which can cause allergic reactions. Therefore, before using suppositories, it is recommended to consult a gynecologist. Candles Pimafucin is contraindicated to use during menstruation and to have sex at the time of treatment.

After oral administration, the suppositories dissolve and have a fungicidal effect. The drug violates the integrity of the membranes of harmful microorganisms, which leads to the death of the fungus. The drug is excreted by the kidneys within 6-8 hours after application.

Use of suppositories for candidiasis during pregnancy

The use of suppositories for candidiasis during pregnancy is a very relevant issue, since many women face this problem due to a weakened immune system. Most drugs are prohibited for use by pregnant women, as there are no reliable data on the safety of drugs for the fetus. Candles from thrush during pregnancy are most preferable, unlike tablets and solutions. As a rule, pregnant women are prescribed Nystatin or Pimafucin, since they can be used from the first trimester. Another effective drug is Clotrimazole suppositories, but they are used with extreme caution, since they are prohibited in the first trimester and undesirable in the next.

Among the local drugs for candidiasis during pregnancy, women are prescribed:

  • Pimafucin.
  • Nystatin.
  • Primafungin.
  • Vagical.

These candles are allowed to be used from the first trimester, as they are safe for both the expectant mother and her baby. In addition to the use of suppositories, candidiasis is treated with combined drugs. These include the McMirr drug complex, with the active ingredients nitstatin and nifuratel. Terzhanin is also prescribed for pregnant women, but it can only be used from the second period of pregnancy.

Contraindications to the use of suppositories from candidiasis

Contraindications to the use of suppositories from candidiasis directly depend on the active substances that make up the suppositories. First of all, it is worth noting that any vaginal suppositories for candidiasis are contraindicated during menstruation. If the treatment cannot be stopped, then the woman is prescribed rectal suppositories.

The main contraindication to the use of suppositories for candidiasis is the individual intolerance to the components of the drug, and especially the active ingredients. If the patient has allergic reactions or hypersensitivity to at least one component, then the drug is not used. During therapy, it is contraindicated to wear synthetic and tight underwear. It is necessary to follow all the rules of intimate hygiene, do not use chemicalized and flavored pads and intimate hygiene products that worsen the symptoms of the disease.

, , ,

Side effects of suppositories from candidiasis

Side effects of suppositories from candidiasis are rare, since suppositories are topical drugs. But manufacturers warn patients that long-term treatment that exceeds the recommended or large dosages of the drug can cause a number of side effects.

Most suppositories are low toxic, so side effects are manifested in the form of minor allergic reactions on the skin: itching, hyperemia, rash. But there are also toxic suppositories, the use of which can cause not only adverse allergic reactions, but also nausea, vomiting, chills, diarrhea, fever, and more. To eliminate side effects, it is recommended to reduce the dosage of the drug. After discontinuation of the drug, all side effects disappear within 72 hours.

Treatment of candidiasis with candles

Treatment of candidiasis with suppositories is a local therapy for a fungal disease. The treatment process must be approached comprehensively. Candles and any other preparations for candidiasis are selected individually for each woman. The advantage of suppositories over other forms of preparations is that they relieve signs of the disease in the first days of use. But after the disappearance of unpleasant symptoms, the course of treatment still needs to be continued. Since incomplete treatment can cause chronic candidiasis, which is quite difficult to cure. Treatment of candidiasis with candles allows you to get rid of not only the symptoms of thrush, but also completely eliminate the yeast fungus.

  • Some drugs for candidiasis must be used with extreme caution, as they cause a number of side effects and disrupt the vaginal microflora. These medicines include: suppositories Polygynax and Terzhinan. Candles Ketoconazole are effective for any form of candidiasis. But due to the many side effects and contraindications, they are not often used.
  • Candles Nystatin fight only with a fungal infection, but in relation to bacteria and viruses, the drug is inactive. This drug is not effective in the treatment of chronic thrush, since Candida fungi develop immunity to the drug. Prolonged use of Nystatin leads to violations of the vaginal microflora. Nystatin is recommended to be used simultaneously with Macmirror suppositories, as they enhance the effect of the first.
  • Treatment of thrush using suppositories can be carried out with broad-spectrum drugs. These drugs include Ginezol. Candles are used to treat recurrent thrush. Both partners must be treated with this drug

It is recommended to use suppositories for candidiasis at bedtime. The suppository must be placed deep into the vagina. Body temperature will allow the candle to melt, and the active substances will penetrate the mucous membrane, providing a therapeutic effect and eliminating the symptoms of the disease.

, , , , ,

Candles from intestinal candidiasis

Candles for intestinal candidiasis are drugs that help eliminate an intestinal infection caused by harmful microorganisms. Intestinal infections cause severe pain and discomfort. Intestinal candidiasis is a type of dysbacteriosis, which is caused by opportunistic fungi. In each person, these fungi are present in the intestines, but in small quantities, without harming the body.

A healthy intestinal microflora independently produces substances that prevent the reproduction of fungi and have antibacterial activity. Intestinal candidiasis occurs when the immune system is unable to prevent the reproduction of harmful microorganisms or there are too many of them. The causative agents of candidiasis are yeast-like fungi Candida, of which there are more than 170 species. Fungi are everywhere: in fruits, vegetables, household utensils, soil and of course in the human body.

  • For the treatment of intestinal candidiasis, it is necessary to use drugs that are not absorbed from the intestinal cavity. The ideal option is rectal and vaginal suppositories. A doctor should prescribe suppositories for intestinal candidiasis, indicating the dosage and duration of use. In addition, it is the doctor who will be able to control the effectiveness of the treatment, since some patients experience allergic and dyspeptic disorders. Treat intestinal candidiasis with the help of such suppositories: Pimafucin, Nystatin and antifungal antibiotics in tablets.
  • Pimafucin is an effective antifungal drug that is approved for use during pregnancy and lactation. Treatment of intestinal candidiasis is long and may take more than one year of therapy.
  • The use of suppositories from candidiasis helps to prevent the development of a generalized form of the disease. The main criterion for cure is a negative culture test for fungi and, of course, the absence of symptoms of the disease. In some cases, in order to achieve a stable therapeutic effect, antimycotic treatment is carried out.

In addition to the main therapy, the patient is given additional symptomatic treatment. To do this, use antispasmodics, laxatives, absorbents, drugs to increase the protective properties of the immune system, multivitamins. Mandatory is the prevention of intestinal candidiasis. Prevention is a complete exclusion of factors that provoke the development of candidiasis. Do not forget about timely visits to doctors at the first symptoms of the disease. It is mandatory to follow a diet, that is, a balanced diet that will prevent the appearance of intestinal candidiasis.

Names of suppositories from candidiasis

Read also:

  • A complete list of suppositories from thrush
  • Sea buckthorn suppositories for thrush

When choosing drugs for thrush, you need to know that there are single-component and multi-component suppositories.

  • Single-component preparations contain one antifungal substance, such drugs include Clotrimazole, Nystatin, Natamycin, Ketoconazole, Gino-Dactanol, Zalain, Ginesol7 suppositories.
  • The second group of drugs for local treatment of candidiasis is combined or multicomponent suppositories. They are effective both in the treatment of thrush and other genital infections. These drugs include: Livarol, Terzhinan, Klion-D, Polygynax. The main advantage of suppositories is a wide spectrum of action. But such drugs are contraindicated for pregnant women in the first trimester and during lactation.

In order for the treatment of candidiasis to be really effective and end with a stable remission of the disease or complete recovery, it is necessary to choose the right drug. Consider the most effective candles for candidiasis:

  • Livarol

The active substance of the suppositories is ketoconazole, an antibiotic from the imidazoledioxolane group. The drug has fungistatic and fungicidal action. Candles are active against yeast-like fungi Candida spp., Pityrosporum spp., As well as dermatophytes, staphylococcal and streptococcal infections.

Livarol is used to treat recurrent vaginal candidiasis, acute thrush and to prevent fungal infections with a weakened immune system. The course of treatment lasts from 3-5 days, one suppository is used at bedtime. And in chronic candidiasis, treatment can last up to 10 days. The drug is contraindicated for allergic reactions to the active substance of suppositories and in the first trimester of pregnancy. Side effects are manifested as nausea, dizziness, irritation and burning of the genitals.

  • Ginezol 7

Suppositories have an active substance - miconazole, which has antifungal activity. The drug has an antibacterial effect against gram-positive microorganisms. Candles quickly eliminate the painful symptoms of candidiasis (itching, burning, redness). The drug has limited systemic absorption. 8 hours after application, 90% of the drug remains in the vagina.

Candles are used to treat vulvovaginal candidiasis and secondary infections. The duration of treatment is individual for each patient and can be from 7 to 14 days of using suppositories. They put suppositories from candidiasis twice a day, in the morning and in the evening, until the symptoms of the disease disappear completely. The drug is contraindicated for use during lactation and pregnancy. Adverse symptoms are rare and usually manifest as minor allergic reactions. Suppositories are contraindicated in case of hypersensitivity to the components of the drug and in case of vaginal herpes.

  • clotrimazole

Local antifungal drug from the group of imidazole derivatives. Clotrimazole has a wide spectrum of activity, which covers almost all pathogenic fungi that cause infections. Suppositories are effective in the treatment of: dermatophytes and dermatophytic fungi, blastomycosis and molds, Nocardia actinomycetes. Small doses of the drug have a fungistatic effect, and large doses have a fungicidal effect.

Suppositories have antimycotic, antibacterial, antiamebic and antitrichomonas action. The main indications for the use of the drug: urogenital candidiasis, skin mycoses, blastomycetes, mold fungi, secondary skin infection. The course of treatment can last up to 4 weeks, the drug is used 1-2 times a day. Side effects are manifested in the form of allergic reactions. Candles are contraindicated in case of individual intolerance to the components of the drug and during the first trimester of pregnancy.

  • Terzhinan

Complex antifungal drug for the treatment of gynecological diseases. The drug has antibacterial activity, is active against anaerobic flora, has a trichomonacid effect. Candles Terzhinan used to treat candidiasis, vaginitis and vaginosis of bacterial etiology. The drug is used to prevent purulent-inflammatory complications before and after surgical interventions in the pelvic area.

Vaginal tablets are inserted deep into the vagina. The duration of continuous treatment takes 10 days, one suppository is used per day. Side effects of the drug appear as allergic reactions that go away on their own. Terzhinan is not used in case of intolerance to the components of the drug and in the first trimester of pregnancy.

  • Viferon

A drug with immunomodulatory, antiviral and antiproliferative properties. Suppositories are used to treat various infectious and inflammatory diseases. Candles are effective in the treatment of candidiasis, herpes, chlamydia and a number of other diseases. The dosage of suppositories is selected by the attending physician, individually for each patient. In the treatment of candidiasis, the course of treatment takes from 5 to 10 days, and the preventive course of treatment is carried out 5 days after the main one.

Side effects of suppositories cause allergic skin reactions that disappear 72 hours after the drug is discontinued. Candles are contraindicated in the first trimester of pregnancy and with individual intolerance to the components of the drug.

  • Zalain

Antifungal drug for topical use. The active substance of the suppositories is sertaconazole. The drug has a fungicidal and fungistatic effect on a wide range of yeasts and fungi. Thanks to the complex effect on the cells of harmful microorganisms, the number of relapses of the disease decreases. Sertaconazole has antifungal activity against a wide range of fungi. When applied topically, the active substance is not absorbed into the systemic circulation.

Vaginal suppositories are used for local treatment of infectious lesions of the vaginal mucosa. The drug is used to treat vaginal candidiasis and mixed infections of the vagina. Suppositories are used once a day, at bedtime. The duration of treatment is individual for each patient and is determined by the attending physician. In addition to the main course of treatment, after seven days it is necessary to carry out prophylactic. The drug does not cause side effects, as it is low toxic. Candles are contraindicated during pregnancy and with individual intolerance to the components of the drug.

  • Lomexin

An effective drug with antifungal and antibacterial action. The drug is active against fungal infections, pathogenic yeasts, molds and gram-positive bacteria. Indications for the use of the drug: genital candidiasis, ringworm, skin candidiasis, fungal infections, vaginal trichomoniasis.

Put candles before going to bed, one after three days, for 10 days. A second course of treatment can be done after 2 weeks. Side effects of the drug are manifested in the form of allergic reactions and burning. Candles are contraindicated in case of individual intolerance to the components of the drug and during pregnancy.

Dosage and administration

The method of administration and doses of drugs for the treatment of candidiasis are established by the attending physician. Only a gynecologist can choose effective suppositories, the required dosage and duration of treatment. The dosage depends on the symptoms of thrush and its type. If we are talking about intestinal candidiasis, then the treatment is quite long and the use of one suppository will not help in eliminating the symptoms of the disease. But with vaginal candidiasis, even one candle of an effective drug can stop a fungal disease. As a rule, the course of treatment lasts from 3 to 14 days. 1 or 2 suppositories can be used per day, depending on the symptoms of thrush.

The method of application depends on the type of suppositories, that is, rectal or vaginal suppositories. Rectal suppositories are inserted into the rectum, and vaginal suppositories are inserted into the vagina. It is recommended to put candles in a prone position or another comfortable position. The suppository must be inserted deep enough, both into the rectum and into the vagina. It is most convenient to use the drug before bedtime. The use of candles before bedtime allows you to achieve maximum effectiveness. Medicinal substances are maximally absorbed into the mucous membrane and allow you to avoid trouble with clothes smeared with a melted suppository. After the introduction of the suppository, it is recommended to cover the vagina with a cotton swab. This will prevent leakage of the melted suppository. As a rule, the active ingredients of suppositories are absorbed within 30 minutes.

It is necessary to use suppositories for candidiasis in accordance with the established course of treatment. Symptoms of the disease may disappear a few days after the application of suppositories. But it is impossible to completely cure diseases in such a short period of time. Abandoned half-way treatment leads to the fact that candidiasis takes a chronic form and can even lead to tolerance of the fungus to the drugs used.

, , , ,

The interaction of candles from candidiasis with other drugs is possible only with the permission of the attending physician. The doctor diagnoses the disease, takes swabs and prescribes a course of treatment. For the treatment of candidiasis, both topical treatments, that is, suppositories, tablets, ointments, and solutions for intravenous administration, can be used.

Consider an example of the interaction of candles from candidiasis Clotrimazole with other drugs. Suppositories Clotrimazole can inhibit the action of other drugs used topically to treat a fungal disease. The drug slows down the action of polyene antibiotics such as Nystatin and Natamycin. If Clotrimazole is used with Dexamethasone, then this significantly inhibits the antifungal effect of suppositories. And the concentrations of the propyl ester of p-hydroxybenzoic acid enhance the antimycotic properties of suppositories from candidiasis.

]

The name of the suppositories from candidiasis The cost of the drug Nystatin from 10 UAH. Clotrimazole from 15 UAH. Ketoconazole from 20 UAH. Klion-D from 60 UAH Polygynax from 70 UAH. Zalain from 72 UAH Lomeksin from 75 UAH. Pimafucin from 80 UAH Terzhinan from 85 UAH Viferon from 110 UAH Natamycin from 117 UAH. Gino-Dactanol from 130 UAH Livarol from 148 UAH Ginezol 7 from 210 UAH

All the above prices are indicative and depend on the pharmacy where the suppositories are sold, the manufacturer of the drug, the number of suppositories in the package and their dosage.

Candidiasis suppositories allow you to quickly and with minimal discomfort eliminate a fungal disease. A wide pharmaceutical selection of suppositories for the treatment of thrush makes it possible to cure any form of the disease or to carry out its prevention. It is not recommended to use candles on your own, as this can cause uncontrolled adverse reactions and worsen the symptoms of thrush. Only a doctor is able to choose effective suppositories for candidiasis that will effectively cure thrush or transfer it to the stage of long-term remission.

Antifungal drugs in gynecology are used quite often, especially in recent times.

fungus symptoms

Probably, every person in his life at least once faced with such an unpleasant disease as a fungus. It can settle on various parts of the human body: on the skin, hair, nails, or even on the reproductive organs. Some of them do not bring any harm to a person and do not cause discomfort, while others make themselves felt as soon as suitable conditions for development appear:

  • a person's immunity has decreased and the body has become less protected;
  • an oncological disease has arisen;
  • there was a serious violation of the microflora.

If the fungus has settled on the female reproductive organs, then this problem is called thrush. If a woman has never encountered such a problem in her life, then she is incredibly lucky. When such a fungal infection occurs, the following symptoms appear:

  • severe itching;
  • redness;
  • vaginal discharge that is curdled, white or creamy in color, and foul-smelling.

These are the signs of a fungus that occurs on the genitals. This disease has been worrying humanity for many years, because even in ancient Greece, thrush was mentioned in numerous treatises of medical origin, but then it had a different name.

In the presence of such symptoms, you should immediately contact a specialist and begin treatment. To do this, use various kinds of antifungal drugs that will help get rid of an unpleasant disease and constant discomfort.

Antibiotics in gynecology

To date, there are a lot of drugs that can help cure the fungus. They can be expensive or cheaper, in the form of tablets, suppositories, ointments, creams, etc. It is necessary to select medicines against thrush only after consulting a specialist, because it is he who will tell you which remedies will be most effective in your case.

At the same time, it will allow you to make a choice faster. At the moment, there are a huge number of drugs that use the presence of a fungus for inflammation.

The most common group of medicines against fungus are antimicrobial agents, which were used by our grandmothers. They contain in their composition a substance such as Nystatin. Most often, inexpensive bright yellow tablets, Nystatin, can be used to treat thrush. Taking them orally or in the form of vaginal suppositories solved this problem.

Quite often, such drugs are used in suppositories, such as Terzhinan or Polygynax. They are, of course, more expensive, but still popular because they are quite convenient and easy to use. The only drawback that Nystatin has is that if you use antifungal drugs of this type for a long time, the body begins to get used to it, and their effectiveness further decreases significantly.

Flucanazole belongs to the 2nd group of drugs. These drugs are of a systemic type, which is available in the form of tablets or capsules. They must be taken exclusively by mouth. There are other effective analogues of this tool. The most popular are Diflucan, Mikomax, Mikosist. They can be found in every pharmacy, not only in tablets, but also in the form of a special solution for intravenous administration into the body with thrush. The drug Fluconazole is widely used not only for the treatment of gynecological problems, but also for fungal infections in chemotherapy and radiotherapy for oncological diseases, AIDS. The negative point in this case is that the agent negatively affects the liver tissue (toxic effects), but these changes are reversible. After the treatment of thrush is completely completed, after a while the liver cells begin to recover on their own.

Itraconazole is drugs such as Itracon, Rumikoz, Irunin. You can find them only in the form of tablets. Unfortunately, candles for local use are not produced. In this case, the fungus can be cured in about 3 days.

Clotrimazole and medicines that are made on its basis - Candiderm or Candide. Recently, they are very often used for a wide variety of fungal infections. You can find antifungal medicines of this type in the form of tablets and suppositories, gels, creams, ointments, or even powder. The huge advantage of these drugs is that they act not only on the fungus, but also on other pathogenic microflora, preventing it from developing further and killing it. If used only as a topical application, then the drugs do not enter the bloodstream, over time there is no accumulation in the soft tissues, and in the place where the agent was applied, it is in the highest concentration.

Ketoconazole preparations - Livarol, Nizoral. They can be purchased in almost every pharmacy in the form of a gel, suppositories, shampoo or tablets. These medicines show an excellent result during the treatment of thrush or the fleecy part of the head.

Separately, it is worth paying attention to drugs such as Pimafucin and Primafungin. The composition of these drugs contains a large amount of Natamycin, which is the active substance.

Natamycin is one of the substances that have a narrowly targeted effect, namely, it is able to cure only Candida-type fungus.

In most pharmacies, sick women can buy these drugs in the form of a cream, suppositories, gel or tablets.

Another effective group of antifungal drugs is Clomegel. It is one of the products for vaginal use. The active substances of Clomegel are Clotrimazole and Metronidazole.

Its very good analogue is the Macmirror complex. The active substances in it are Nystatin and Nifuratel. You can find medicines in the form of vaginal suppositories or in the form of a cream.

Antifungal medications: what to expect?

Modern drugs are quite strong and can solve the problem with the fungus in just 1-3 days. This is the feature that distinguishes modern medicine from the medicine of our grandmothers. For example, we can compare the new antibiotics in gynecology, nnystatin, which must be taken for at least a week to get a positive result.

It is worth noting that no matter what the drugs are, they will have contraindications and, of course, at least minimal side effects. In this regard, only a specialist should prescribe an antifungal drug in gynecology and only after a thorough examination of the woman. As a general rule, systemic drugs are not recommended for pregnant women or those who are breastfeeding. Tablets to be taken orally are used only when there is no positive result from local treatment, for example, if the disease has already taken a chronic form.

If we talk about side effects, then they can manifest themselves in the form of problems with the digestive system of a woman, namely:

  • diarrhea;
  • nausea;
  • vomit;
  • sometimes taste disturbances can occur.

In this regard, in no case should you choose your own medicines. The same can be said about the way it is introduced into the body. Only a specialist can determine which antifungal agent will be effective in your case.

The fungus of the reproductive system in a woman is a very serious problem, the treatment of which should in no case be delayed. You should consult a doctor immediately after the first signs of the disease appear. Otherwise, quite serious complications can occur, up to the development of infertility.

It is also worth considering the fact that thrush is sexually transmitted, so there is a high risk of infection and your sexual partner. Take care not only about your health, start treatment on time!

In most cases, a fungal infection in women is accompanied by symptoms such as pain, redness, burning and itching. Antifungal suppositories can help to quickly eliminate them. And some types of drugs have such powerful properties that they can get rid of unpleasant symptoms the first time.

Often used remedies help to quickly not only defeat the infection, but also restore the microflora of the body. Candles are inserted deep into the vagina, coping with the fungus in the mucosa, contributing to its death. There are two forms of drugs:

  • Antifungal vaginal suppositories - require deep insertion into the vagina, usually discharged for 10 days.
  • Antifungal rectal suppositories - used in case of intestinal damage. If there are certain indications for use, during critical days the drug is placed in the anus.

When treating with candles, several points must be considered:

  • Before going to the pharmacy for candles, you should take tests and consult with a specialist.
  • Self-medication in this case is absolutely not an option, it can lead to a deterioration in well-being.
  • The wrong approach or inappropriate doses can lead to the development of immunity in the pathogen.

Antifungal suppositories in gynecology

A yeast-like fungus of the genus Candida is part of the human body. It tends to actively multiply and develop due to a weakened immune system. It affects the mucous membrane, accompanied by unpleasant symptoms: pain, burning, redness and itching.

Antifungal suppositories help:

  • get rid of the unpleasant symptoms of a fungal infection;
  • destroy the infection
  • stop the process of reproduction;
  • show restorative properties;
  • say goodbye to curd-like secretions.

The female body recovers due to the effects of active antifungal drugs, leading to various results:

  • The living conditions of bacteria are violated, which does not allow them to continue to exist and develop.
  • The fungal cell membrane is affected by the agent, the growth of the microorganism is inhibited. Since the development of the organism is disturbed, reproduction becomes impossible.

Application rules:

It is necessary to keep the drug in the refrigerator, since the high temperature of the human body simply melts it. Rectal and vaginal suppositories differ in use, but they also have certain similarities:

  • treatment is carried out by both partners, even if the young man has not been found to have an infection;
  • before the introduction it is necessary to perform hygiene procedures; they should also be regular throughout life, as this helps reduce the risk of catching an infectious disease again;
  • before the procedure, you should clean the intestines when it comes to rectal suppositories;
  • wash your hands, but in no case do not use irritants;
  • there is a risk of staining underwear, so it is advisable to use daily pads or clothes that you don’t mind.

To properly insert a rectal suppository:

  1. we lie down on our side, we completely straighten one leg, we pull the other to the chest;
  2. Vaseline should be used to ensure easy penetration, sliding;
  3. pull one of the buttocks;
  4. the drug is administered very carefully so as not to damage the internal organs (distance - 5 centimeters);
  5. connect the two buttocks together and strain strongly so that the remedy can linger and act;
  6. in this position should be about five minutes;
  7. get up, wash your hands, use underwear with already prepared daily.

To properly insert a vaginal suppository:

  1. lie down on your back, pulling your legs to your chest;
  2. gently push the vagina apart and inject the drug as carefully as possible, gradually deepening into the hole (nails should be absent, otherwise there is a chance of hurting and damaging internal organs);
  3. lie down for about 20 minutes in this position, giving time for the agent to dissolve and act;
  4. get up and use linen with a pad;
  5. Wash the hands.

Data group of medicinal suppositories

In the field of gynecology, antifungal drugs are used. They are intended for use in the prevention and treatment of infections. Antifungal suppositories are highly effective, help to quickly get rid of the disease. They are divided into groups:

  1. polyene antibiotics. These include "Nystatin" and "Natamycin", which kill fungi, preventing their reproduction.
  2. Azoles - "Clotrimazole", "Ketoconazole", which stop the growth of fungi.
  3. Antibacterial agents, which include Hexicon and Betadine, which act depressingly on fungi and genital infections.

Candidiasis, often observed in women, is accompanied by many gynecological problems. In the fight against them, combined preparations with an antifungal effect, supplemented with other substances, are used:

Other broad-spectrum antifungals

To combat infectious diseases, pharmacists have developed drugs that have a disinfecting effect on mucous membranes, skin integuments and all vital organs. This is a small group belonging to a wide range of antifungal agents.

Pharmacology of antifungal drugs

The pharmacology group is divided into drug classes. It includes polyenes, imidazoles, triazoles, echinocandins and others.

Antifungal drugs differ in different pharmacological orientations.

  • Polyenes are drugs that destroy the spread of infection of fungal etiology. They bind to the basis of stem cells - ergosterol, violate the integrity of the cell, which adversely affects it.

These include: "Nystatin", used to get rid of infections caused by the yeast Candida. "Amphotericin B" - he successfully fights many infectious diseases.

  • Imidazoles and triazoles are representatives of the category of antifungal agents belonging to the group of azoles. The mechanism of action is aimed at slowing down the enzymatic reaction of lanosterol 14-alpha-demethylase. The drug has a destructive effect on pathogenic cells, increasing the permeability of their walls. The activity of drugs depends on which drug they belong to.

The use of imidazoles is widespread. They are used to treat fungal diseases caused by Candida yeast.

"Clotrimazole" is an effective remedy designed to suppress vaginal candidiasis. It copes with dermatophyte infections, it is prescribed for ringworm. "Ketoconazole" is used in the treatment of fungal diseases of the mucous membranes.

"Fluconazole" - a reliable drug with a highly specific effect, is used in the event of cryptococcal infections, prevents the development of candidiasis.

"Itraconazole" - effective when used in the fight against mucocutaneous candidiasis. It suppresses dermatophyte infections, including lichen and dermatophytosis.

"Voriconazole" - inhibits the action of scedosporium and fusarium fungi, through which invasive aspergillosis and many other infectious diseases are successfully treated.

  • Echinocandins. Caspofungin and Micafungin belong to this category of funds. Destructively acting on the walls of fungal cells, they successfully cope with infections. "Caspofungin" is used for problems associated with invasive aspergillosis, invasive candidiasis is treated.

More about polyenes

Polyenes are used in case of complications in mycosis, as a rule, they are prescribed to people with unstable and weakened immunity. While most experts distinguish natamycin into the group of macrolides. This tool is used for various purposes, and there are a large number of them.

But, as a rule, it is used in order to painlessly correct various fungal infections. The drug easily destroys fungal structures, destroying cell membranes.

Specialists prescribe drugs containing natamycin if the patient has signs of thrush or skin candidiasis. These drugs include Pimafucin and Ecofucin.

These funds are produced in different forms:

  • oral tablets;
  • candles for the vagina;
  • creams.

Due to the special action of the active substances of the antifungal agent, it can be used even during pregnancy.

"Amphotericin-B" is used if the patient has signs of deep mycosis, damage to any organs, or the formation of fungal structures on the skin. This drug is produced both in special ampoules for internal use, and in the form of a cream.

If fungal formations of the Candida species occur, experts recommend using Nystatin and Levorin. When using them, you should also drink a course of penicillin antibiotics (if you are not allergic).

The analogue of "Amphotericin-B" is "Mikopegin", so it can be used for exactly the same diseases and fungal formations. "Mikopegin" is dangerous if a woman is carrying a fetus, and is also contraindicated in children under 10 years of age due to the high toxicity of active substances.

Antibiotics based on synthetic additives

Synthetic preparations are used for external application for fungal skin diseases, they can also be used for systemic treatment of fungal infections and candida. Such agents are azoles, allylamines and pyrimidines.

The inputs are subdivided into imidazoles and triazoles. In turn, triazoles are divided into the following groups:

  1. "Voriconazole" - available in tablet form. The active substances are Vfend, Vikand or Biflurin. If there are large and deep fungal formations on the body or suspicion of the formation of fungi after an organ transplant operation, the doctor will advise you exactly this drug.
  2. "Itraconazole" - are available in the form of capsules for internal use. The active substances are orungal, orunite, itrazol, itramikol, irunin or rumikoza. Used for damage to nails or superficial skin.
  3. "Fenticonazole" is one of the latest developments of scientists to combat fungal infections. Produced in the form of oral and vaginal ampoules, as well as ointments.

There are also other little-known analogues of these drugs, you can familiarize yourself with them and find out the prices on the vastness of our website, the description is placed next to the photo of the product.

Synthetic substances for external use

These drugs include medicines used for superficial treatment of the skin or nails. In order to get rid of the fungus on the nail, you will need to remove the top layer of the formation and only then apply the product. As a rule, such drugs are produced in the form of a cream and contain sulfur, one of these is Naftalan.

The drugs with the names "Lotriderm", "Sangviritrin", "Travocort" also show themselves well. Now nail polishes containing antifungal substances are very popular. The varnish forms a film of the color you need, which also helps in the treatment of the fungus.

If a fungal infection has appeared in the scalp, special shampoos with active substances (Nizoral and Cynovit) should be used. For the treatment of formations located near the visual organs, special eye drops are used (Ketoconazole, Fluconazole, Itraconazole).

How helpful was this post?

Click on a star to rate it!

Submit Rating